Wei Fan, Professor, doctoral supervisor, Top Young talents in Yunnan Province, winner of Huo Yingdong Young Teachers Fund, Director of the Dengzhanhua Experimental Station of the Modern Agricultural Industry System of Traditional Chinese Medicine in Yunnan Province. He is mainly engaged in the ecological cultivation of traditional Chinese medicine, the restoration of soil barrier factors and the control of heavy metals. He presided over 3 National Natural Science Foundation projects, participated in 9 national and provincial projects, published 34 papers (24 SCI papers) as the first or corresponding author, bred 7 new varieties of medicinal plants, and authorized 12 patents (5 invention patents). He is currently the guest editor of frontier in plant science.

Projections

1. National Natural Science Foundation of China “Functional analysis of cadmium uptake and transport in Panax notoginseng mediated by natural resistance-associated macrophage proteins (Nramp) family genes（31960634）”,  2020-2023

2. National Natural Science Foundation of China “Study on the molecular mechanism regulating tomato fruit nutrition by acetylation-mediated oxalate degradation (31760584)” , 2018-2021

3. National Natural Science Foundation of China “Structural and functional analysis of rice bean VuSTOP1 in regulating proton and aluminum resistance in plants (31501827) ” , 2016-2018

4. Major Science and Technique Programs in Yunnan Province “Key technology and demonstration of organic Chinese herbal medicine production under forest（202102AE090042）”, 2021-2023

5. Major Science and Technique Programs in Yunnan Province “Production technology innovation and application of high quality Panax notoginseng（202102AA310048）”, 2021-2023

6. National Key Research and Development Plan “Ecological planting technology and health product development of Panax notoginseng”（2017YFC1702501）”, 2018-2021

7. Major Science and Technique Programs in Yunnan Province “Research on key technologies for the development of new resource species Moringa oleifera and Maca (2017ZF004)” 2017-2020

8. Major Science and Technique Programs in Yunnan Province “Construction and application of technical system for overcoming continuous cropping obstacles of Panax notoginseng (2016ZF001) ”, 2017-2020

9. Chinese Academy of Engineering - local cooperation project “Research on green development strategy of natural medicine under forest in Yunnan（2019YNZD1）”

10. Major Science and Technique Programs in Yunnan Province “Study and demonstration on wildlife tending of Marsdenia tenacissima (2016RA009)” , 2016-2018

11. Major Science and Technique Programs in Yunnan Province “Key technology and industrialization of processing technology of Polygonatum polyflora (2016RA030)” , 2016-2019

12. Standardization Project of National Traditional Chinese Medicine “Standardization construction of breviscapine for injection(ZYBZH-C-YN-59) ” , 2016-2019

Publications

1. Chen WW, Tang L, Wang JY, Zhu HH, Jin JF, Yang JL*, Fan W*. Research advances in the mutual mechanisms regulating response of plant roots to phosphate deficiency and aluminum toxicity. International journal of molecular Sciences. 23, 1137.

2. Li Y, Lin Y, Jia B, Chen G, Shi HN, Xu R, Li XJ, Tang JR, TangQY, Zhang GH, Yang JL, Fan W*, Yang SC*. 2022. Transcriptome analysis reveals molecular mechanisms underlying methyl jasmonate-mediated biosynthesis of protopanaxadiol-type saponins in Panax notoginseng leaves. 65:29-41.

3. Lou HQ#, Fan W#, Jin JF, Xu JM, Chen WW, Yang JL*. Zheng SJ. 2020. A NAC-type transcription factor confers aluminium resistance by regulating cell wall‐associated receptor kinase 1 and cell wall pectin. Plant, Cell & Environment. 43: 463-478.

4. Wang ZQ, Zhao QM, Zhong XT, Xiao L, Ma LX, Wu CF, Zhang ZS, Zhang LQ, Tian Y*, Fan W*. 2020. Comparative analysis of maca (Lepidium meyenii) proteome profiles reveals insights into response mechanisms of herbal plants to high-temperature stress. BMC Plant Biology. 20:431.

5. Jin JF, Wang ZQ, He YQ, Wang JY, Li PF, Xu JM, Zheng SJ, Fan W*, Yang JL*. 2020. Genome-wide identification and expression analysis of the NAC transcription factor family in tomato (Solanum lycopersicum) during aluminum stress. BMC Genomics. 21:288.

6. Tang JR, Lu YC, Gao ZJ, Song WL, Wei KH, Zhao Y, Tang QY, Li XJ, Chen JW, Zhang GH, Long GQ, Fan W*, Yang SC*. 2019. Comparative transcriptome analysis reveals a gene expression profile that contributes to rhizome swelling in Panax japonicus var. major. Plant Biosystems. 154:515-523.

7. Yang JL#, Fan W#, Zheng SJ*. 2019. Mechanisms and regulation of aluminum-induced secretion of organic acid anions from plant roots. Journal of Zhejiang University-SCIENCE B. 20: 513-527.

8. Fan W, Xu JM, Wu P, Yang ZX, Lou HQ, Chen WW, Jin JF, Zheng SJ, Yang JL*. 2019. Alleviation by abscisic acid of Al toxicity in rice bean is not associated with citrate efflux but

depends on ABI5-mediated signal transduction pathways. Journal of Integrative Plant Biology. 61: 140-154.

9. Li XJ, Yang JL, Hao B, Lu YC, Qian ZL, Li Y, Ye S, Tang JR, Chen M, Long GQ, Zhao Y, Zhang GH, Chen JW, Fan W*, Yang SC*. 2019. Comparative transcriptome and metabolome analyses provide new insights into the molecular mechanisms underlying taproot thickening in Panax notoginseng. BMC Plant Biology. 19:451.

10. He SM, Wang X, Yang SC, Dong Y, Zhao QM, Yang JL, Cong K, Zhang JJ, Zhang GH, Wang Y*, Fan W*. 2018. De novo transcriptome characterization of Rhodomyrtus tomentosa leaves and identification of genes involved in α/β-Pinene and β-caryophyllene biosynthesis. Frontiers in Plant Science. 9:1231.

11. He SM, Liang YL, Cong K, Chen G, Zhao X, Zhao QM, Zhang JJ, Wang X, Dong Y, Yang JL, Zhuang GH, Qian ZL, Fan W*, Yang SC*. 2018. Identification and characterization of genes involved in benzylisoquinoline alkaloid biosynthesis in Coptis species. Frontiers in Plant Science. 9:731.

12. Chen WW, Xu JM, Jin JF, Lou HQ, Fan W*, Yang JL*. 2017. Genome-wide transcriptome analysis reveals conserved and distinct molecular mechanisms of Al resistance in buckwheat (Fagopyrum esculentum Moench) leaves. International Journal of Molecular Sciences. 18: 1859(IF: 4.556).

13. He SM, Song WL, Cong K, Wang X, Dong Y, Cai J, Zhang JJ, Zhang GH, Yang JL, Yang SC*, Fan W*. 2017. Identification of candidate genes involved in isoquinoline alkaloids biosynthesis in Dactylicapnos scandens by transcriptome analysis. Scientific Reports. 7: 9119 (IF: 3.998).

14. Xu JM#, Fan W#, Jin JF, Lou HQ, Chen WW, Yang JL, Zheng SJ. 2017. Transcriptome analysis of Al-induced genes in buckwheat (Fagopyrum esculentum Moench) root apex: new insight into Al toxicity and resistance mechanisms in an Al accumulating species. Frontiers in Plant Science.8:1141.

15. Xiao C#, Fan W#, Du SJ, Liu LZ, Wang CL, Guo MZ, Zhang LW, Zhang M, Yu LJ. 2017. A novel glycosylated solution from Dioscorea zingiberensis C.H. Wright significantly improves the solvent productivity of Clostridium beijerinckii. Bioresource Technology. 241: 317-324.

16. Fan W, Chang WJ, Liu XW, Xiao C, Yang JL, Zhang ZL. 2017. Identification of up-regulated genes provides integrated insight into salt-induced tolerance mechanisms in Sesuvium portulacastrum roots. Acta Physiologiae Plantarum.39:86.

17. Fan W#, Hai M#, Guo Y#, Ding Z, Tie W, Ding X, Yan Y, Wei Y, Liu Y, Wu C, Shi H*, Li K*, Hu W*. 2016. The ERF transcription factor family in cassava: genome-wide characterization and expression analyses against drought stress. Scientific Reports. 6:37379.

18. Lou HQ#, Fan W#, Xu JM, Gong YL, Jin JF, Chen WW, Liu LY, Hai MR, Yang JL, Zheng SJ. 2016. An oxalyl-CoA synthetase is involved in oxalate degradation and aluminum tolerance. Plant Physiology. 172: 1679-1690.

19. Fan W, Xu JM, Lou HQ, Xiao C, Yang JL*.2016. Physiological and molecular analysis of aluminium-induced organic acid anions secretion from grain amaranth (Amaranthus hypochondriacus L.) roots. International Journal of Molecular Sciences. 17: 608.

20. Liu MY, Xu JM, Lou HQ, Fan W*, Yang JL*, Zheng SJ. 2016. Characterization of VuMATE1 expression in response to iron nutrition and aluminum stress reveals adaptation of rice bean (Vigna umbellata) to acid soils through cis regulation. Frontiers in Plant Science. 7:511.

21. Fan W, Lou HQ, Yang JL*, Zheng SJ. 2016. STOP1-like transcription factors: differential roles in aluminum and proton tolerance. Plant Signaling & behavior. 11: e1131371.

22. Fan W#, Lou HQ#, Gong YL, Liu MY, Yang JL*, Zheng SJ. 2015. Characterization of an inducible C2H2-type zinc finger transcription factor VuSTOP1 in rice bean (Vigna umbellata) reveals differential regulation between low pH and aluminum tolerance mechanisms. New Phytologist. 208: 456–468.

23. Fan W, Lou HQ, Gong YL, Liu MY, Wang ZQ, Yang JL*, Zheng SJ. 2014. Identification of early Al-responsive genes in rice bean (Vigna umbellata) roots provides new clues to molecular mechanisms of Al toxicity and tolerance. Plant, Cell & Environment. 37:1586-1597.

24. Fan W, Zhang YL, Zhang ZL*.2009.Cloning and molecular characterization of fructose-1, 6-bisphosphate aldolase gene regulated by high-salinity and drought in roots of Sesuvium portulacastrum. Plant Cell Reports. 28:975-984.